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Enterotoxaemia Vaccine (Type D)

    Definition:-
  • Enterotoxaemia vaccine is a culture of a highly toxigenic strain of Clostridium perforin genes type D grown in an anaerobic medium, and rendered sterile and atoxic by use of formaldehyde solution, I.P. in such a manner that it retains its immunogenic properties. The vaccine is adjuvanted with Potash - Alum.
  • Use:-

  • The vaccine can be used in sheep and goats for protection against Enterotoxaemia type D infection. Vaccination in pregnant ewes and lambs is advised for effective immunisation.
  • Doses and Administration:-

  • Sheep and Goats
  • 2.5 ml. subcutaneously in loose fold of skin at post axillary region
  • Cattle and Buffaloes
  • 5 ml. subcutaneously on side of the neck
  • In the first year of life primary immunisation is done at 3rd month, 6th month, and 12th month of age.Yearly vaccination is done thereafter.Under field conditions, where previous vaccination status is not known, booster vaccination may be done after 15 days from 1st vaccination.; vaccination may be done once in a year, in subsequent years.
  • Reactions:-

  • Normally no reactions are noticed. Local tissue reaction may be noticed in the form of small swelling that should subside soon.
  • Immunity:-

  • I It lasts for one year after primary immunisation.
  • Precautions:-

    • The bottle should be shaken well before use.
    • Keep the bottle away from direct sunlight.
    • Gently massage the site of inoculation, after administration of the vaccine.
    • The bottle opened once should be utilised fully on the same day.
    • Sterile syringes and needles should be used.
    • Use of antihistaminics or similar drugs is advised in case of any generalised reaction noticed after vaccination.
    • The separate needle should be used for drawal of vaccine from vial and inoculation.
    • Vaccine vials showing cracks or damaged stoppers should not be used.

Storage:-

  • The vaccine may be stored between 40 C to 80 C. The vaccine can be stored for three years at this temperature. The vaccine may be stored at 220 C to 250 C for a period of six months. Store away from light, in a cool dark place.
  • Packing:-

  • 250 ml. in polypropylene bottle containing 100 doses.