Enterotoxaemia Vaccine (Type C)

Definition:-

• Enterotoxaemia vaccine is a culture of a highly toxigenic strain of Clostridium perfringenes Type C grown in an anaerobic medium , and rendered sterile and atoxic by use of formaldehyde solution,I.P. in such a manner that it retains its immunogenic properties. The vaccine is adjuvanted with Potash - Alum.

Use:-


• The vaccine can be used in sheep and goats for protection against Enterotoxaemia Type C infection. Vaccination in pregnant ewes and lambs is advised for effective immunisation. In Maharashtra, it is mainly used in large animals in Konkan tract.

Doses and Administration:-

• Sheep and Goats
• 2.5 ml. subcutaneously in loose fold of skin at postaxillary region
• Cattle and Buffaloes
• 5 ml. subcutaneously on side of neck
• In the first year of life primary immunisation is done at 3rd month , 6th month, and 12th month of age.Yearly vaccination is done thereafter.
• Under field conditions, where previous vaccination status is not known, booster vaccination may be done after 15 days from 1st vaccination. vaccination may be done once in a year, in subsequent years.

Reactions:-


• Normally no reactions are noticed. Local tissue reaction may be noticed in the form of small swelling in vaccine , which should subside soon.

Immunity:-


• It lasts for one year after primary immunisation.

Precautions:-

• The bottle should be shaken well before use.
• Keep the bottle away from direct sunlight.
• Gently massage the site of inoculation, after administration of vaccine.
• The bottle opened once should be utilised fully on the same day.
• Sterile syringes and needles should be used.
• Use of antihistaminics or similar drugs is advised in case of any generalised reaction noticed after vaccination.
• Separate needle should be used for drawal of vaccine from vial and inoculation.
• Vaccine vials showing cracks or damaged stoppers should not be used.

Storage:-

Packing:-